A new rumor claims that Mark Ruffalo will appear as Bruce Banner in Spider-Man: Brand New Day. While I think the Hulk being in the next Spider-Man movie goes away from the street-level story, which I hope it will adapt, there is a precedent for how he could play a role in the film, as the Hulk could who Peter Parker was after Doctor Strange's spell, as something similar happened in the comics. I think that would be an exciting twist, and I would be interested in seeing the Hulk and Spider-Man finally work together in the MCU.